7 edition of Chemokines and cancer found in the catalog.
by Humana Press in Totowa, N.J
Includes bibliographical references and index.
|Statement||edited by Barrett J. Rollins.|
|Series||Contemporary cancer research|
|Contributions||Rollins, Barrett J.|
|LC Classifications||RC271.C48 C46 1999|
|The Physical Object|
|Pagination||xii, 320 p. :|
|Number of Pages||320|
|LC Control Number||98048424|
Chemokines: Angiogenesis and Metastases in Lung Cancer. Robert M. Strieter. Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California, Los Angeles, David Geffen School of Medicine, UCLA, Veteran Avenue, 14– Warren Hall, Box , Los Angeles, CA , USA Cited by: A greater understanding of the role of chemokines in coordinating the development and maintenance of mucosal immunity, in addition to the nature of pathological inflammation in the gut, has suggested therapeutic strategies for targeting leukocyte recruitment pathways in Cited by: 9.
Until recently, inflammatory chemokines were viewed mainly as indispensable “gate keepers” of immunity and inflammation. However, updated research indicates that cancer cells subvert the normal chemokine system and these molecules and their receptors become important constituents of the tumor microenvironment with very different ways to exert tumor-promoting by: However, chemokines and their receptors are also important in dendritic cell maturation (2), B (3), and T (4) cell development, Th1 and Th2 responses, infections, angiogenesis, and tumor growth as.
Keywords:Cancer, chemokines, clinical trials, cytokines, immunotherapy, inflammation. Abstract:The response of the body to cancer is not a unique mechanism and has many parallels with inflammation and wound healing. Unresolved inflammation generates a microenvironment favorable for cellular transformation and the growth of cancer cells. CXC chemokines bind to CXC chemokine receptors, of which seven have been discovered to date, designated CXCR C chemokines. The third group of chemokines is known as the C chemokines (or γ chemokines), and is unlike all other chemokines in that it has only two cysteines; one N-terminal cysteine and one cysteine ro: IPR
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Chemokines and Cancer synthesizes a state-of-the-art understanding of the role that chemokines and their receptors play in the pathophysiology of malignancy. It examines the influence of chemokines on a broad array of malignant cells, including their effects on such intrinsic properties as growth and movement, as well as exploring their influence on the host's response to a growing tumor.3/5(1).
The only book available that relates chemokines to cancer, Chemokines and Cancer holds out the promise of novel therapeutic approaches to malignancy through the manipulation of chemokines.
Available in: ines and Cancer synthesizes a state-of-the-art understanding of the role that chemokines and their receptors play in the Due to COVID, Price: $ Chemokines are chemotactic cytokines that mediate Chemokines and cancer book cell chemotaxis and lymphoid tissue development.
Recent advances have indicated that chemokines and their cognate receptors play critical roles in cancer-related inflammation and cancer progression. On the basis of these findings, the chemokine system has become a new potential drug target for cancer : Do Htt, Lee Ch, Cho J.
This book reveals essential roles of the tumor microenvironment in cancer progression and provides a comprehensive overview of the latest research on the role of chemokines in the tumor microenvironment.
The potential of targeting chemokine networks for the treatment of cancer. Inflammation is an essential component of the tumor microenvironment and one of the hallmarks of cancer (1, 2).
Chemokines, are a family of small, secreted, and structurally related cytokines with a crucial role in inflammation and by: These scatterplots of cancer‐specific stress scores from patients with chronic lymphocytic leukemia (N = 92) illustrate log‐normal values for (A) absolute lymphocyte counts (lnALC), (B) tumor necrosis factor α (lnTNFα), (C) interleukin 16 (lnIL‐16), and (D) chemokine (C‐C motif) ligand 3 (lnCCL3) at treatment initiation with the line Cited by: 6.
Chemokines in cancer therapy. Standard first line cancer therapies, such as chemotherapy and radiotherapy, have been demonstrated to, at least partially, rely on their immunostimulatory effects for their therapeutic efficacy. It has been suggested that the specific immune contexture of a tumor can be correlated to clinical outcomes.
Thus, the presence of specific chemokines in the TME may be a Cited by: Chemokines regulate the infiltration of different immune cell subsets into tumours and, as such, these molecules affect tumour immunity and influence therapeutic outcomes in by: Helbig, G., et al., NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4.
J Biol Chem, J Biol Chem, (24): p. Cited by: Breast cancer is a leading cause of cancer-related deaths worldwide, predominantly caused by metastasis. It is generally accepted that the pattern of breast cancer metastasis is largely determined by the interaction between the chemokine receptors on cancer cells and the chemokines expressed at the sites of metastatic disease.
This book is essential for researchers and clinicians interested in cytokines, including anyone working in cancer biology, transplantation, infectious diseases, autoimmunity or bioinformatics.
Show less. The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate immune responses. The book Chemokines and Cancer is very timely, as it addresses an area that has undergone an explosive increase in information in recent years.
The contributions that were selected by the editor, Barrett Rollins, MD, PhD, are reasonable and are written by respected authors in the by: 1. Chemokines and Cancer synthesizes a state-of-the-art understanding of the role that chemokines and their receptors play in the pathophysiology of malignancy.
This volume in the Current Topics in Membranes series discusses the biology of chemokines and their binding partners, chemokine receptors, in normal and disease-related states. Chemokines are small proteins that are important in normal immune responses.
Recent research demonstrates a role for these proteins in a variety of diseases such as heart disease, allergy, asthma, and Edition: 1. The only book available that relates chemokines to cancer, Chemokines and Cancer holds out the promise of novel therapeutic approaches to malignancy through the.
Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the role of chemokines in the tumor microenvironment. Each chapter focuses on the chemokines patterns of expression, their regulation, and their roles in immune cell recruitment, as well as how.
The only book available that relates chemokines to cancer, Chemokines and Cancer holds out the promise of novel therapeutic approaches to malignancy through the manipulation of chemokines and/or their : Humana Press.
Chemokines and Cancer synthesizes a state-of-the-art understanding of the role that chemokines and their receptors play in the pathophysiology of malignancy. It examines the influence of chemokines on a broad array of malignant cells, including their effects on such intrinsic properties as growth and movement, as well as exploring their Brand: Humana Press.
Chemokines and Cancer. All prices are NET prices. VAT will be added later in the : Marco Baggiolini. The book examines in detail fifteen recently identified chemokines and elucidates the role of chemokine function in vivo from animal experiments. Animal models are also used to explore how chemokines operate in a variety of chronic and acute inflammatory diseases and in noninflammatory : Caroline A.
Hébert.Chemokines and stem cell proliferation -- Chemokines and hematopoiesis -- Macrophage inflammatory protein-1[alpha] and stem cell inhibition.\/span>\"@ en\/a> ; \u00A0\u00A0\u00A0\n schema:description\/a> \" Chemokines and Cancer synthesizes a state-of-the-art understanding of the role that chemokines and their receptors play in the.Chemokines (CKs) are a family of small proteins secreted by a great variety of cell types.
Their name (derived from differentiation, infection, autoimmunity, cancer and, in general, in any situation where immune components are involved.
Their role in human immunodeficiency virus (HIV) infection is of special relevance. Introduction.